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|Re: Edmonton: R.I.P. Warcrimes|
< Reply # 66 on 5/17/2010 3:57 PM >
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|Posted by aurelie|
Do the symptoms of methanol poisoning match up with any of your symptoms?
Initial symptoms of methanol poisoning may appear as soon as 12 hours post-ingestion, but usually develop 24 hours after ingestion. These may resemble ethanol intoxication and consist of drowsiness, confusion, and ataxia, as well as weakness, headache, nausea, vomiting, and abdominal pain. Collectively, these symptoms may mimic an alcohol hangover and are due to mild intoxication, caused by methanol itself.
As methanol metabolism proceeds, a severe anion gap metabolic acidosis will develop. Severe metabolic acidosis in conjunction with visual effects are the hallmark of methanol poisoning. Patients usually describe blurred or misty vision, double vision, or changes in color perception. There my be constricted visual field and, occasionally, total loss of vision. Characteristic visual dysfunctions include pupillary dilation and loss of pupillary reflex (Burkhart 1990; Suit 1990).
Further signs and symptoms may be shallow respiration, cyanosis, tachypnea, coma, seizures, electrolyte disturbances, and various hemodynamic changes including profound hypotension and cardiac arrest. There may be mild to profound loss of memory, confusion, and agitation, which may progress to stupor and coma as the severity of the acidosis increases (Suit 1990). In severe cases, death is possible. Surviving patients can be left with permanent blindness or with other neurological deficits (Jacobsen 1997).
[last edit 5/17/2010 3:57 PM by AnAppleSnail - edited 1 times]
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