I have only been through Indiana in passing and never got to UE in that state but I've lived in Detroit my whole life. While there are still literally tens of thousands of abandoned houses, store fronts and smaller industrial structures, many personal favorites (my own and those of others) have either been torn down in recent years or secured.
For instance, the old Eastown and Madison theaters are gone. There was a great hospital and funeral home near each other that have since been sealed off and, last time I checked, the Packard Plant complex was being closely watched by security. I'm not sure about the current state of the Book Cadillac building but I know it was secured at least 10 years ago w/ some possible restoration going on.
Also, Mayor Duggan has stepped up the demolition program for some buildings in the area that have stood vacant for several decades. (Most of those are unsafe, fire damaged shells)
If you do decide to come to Detroit and have an interest in a particular building, I can cruise by it just to check the status quo.
Best of luck!